该基因编码富含亮氨酸的小蛋白多糖 (SLRP) 蛋白质家族的成员。编码的前原蛋白经过蛋白水解加工生成成熟蛋白，在骨骼生长、肌肉发育和再生以及多种组织中的胶原纤维组装中发挥作用。这种蛋白质还可以调节炎症和先天免疫。此外，编码的蛋白质可能导致人类患者的动脉粥样硬化和主动脉瓣狭窄。该基因和相关基因核心蛋白聚糖被认为是基因复制的结果。[RefSeq 提供，2015 年 11 月]

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015]