Acquired immunodeficiency syndrome(AIDS) is an important public health problem in China. In 2005, the first edition of the guidelines for the diagnosis and treatment of AIDS was formulated by the AIDS Professional Group of Society of Infectious Diseases of Chinese Medical Association, which was updated in 2011, 2015, and 2018, respectively. The 2021 edition of the guidelines was revised on the basis of the 2018 edition and updated according to national clinical practice and the latest research results. The new research progress in opportunistic infections, antiretroviral therapy, post-exposure prophylaxis (PEP), pre-exposure prophylaxis (PrEP), whole course management of human immunodeficiency virus(HIV) infection, and prevention of mother to child transmission was updated in this guidelines. In the 2021 edition, the indications, medication regimen, follow-up and monitoring, and precautions of PrEP were introduced in detail.

艾滋病在中国是一个重要的公共卫生问题。2005年中华医学会感染病学会艾滋病丙型肝炎学组制定了第一版《中国艾滋病诊疗指南》，并于2011年、2015年和2018年分别进行了更新。2021年版指南是在2018年版指南的基础上，根据我国临床实践和最新研究结果进行的更新，主要反映了机会性感染、抗反转录病毒治疗、暴露后预防（PEP）、暴露前预防（PrEP）、人类免疫缺陷病毒（HIV）感染全程管理和预防母婴传播方面的最新研究进展。本版指南详细介绍了PrEP的适应证、用药方案、随访和监测以及预防措施。.