IPI、NCCN

2024-07-09 09:06| 来源: 网络整理| 查看: 265

Zhonghua Xue Ye Xue Za Zhi. 2018 Sep; 39(9): 739–744. Chinese. doi: 10.3760/cma.j.issn.0253-2727.2018.09.007PMCID: PMC7342249PMID: 30369184

Language: Chinese | English

IPI、NCCN-IPI及年龄调整的IPI评分系统在弥漫大B细胞淋巴瘤患者中的预后价值比较The prognostic value of the international prognostic index, the national comprehensive cancer network IPI and the age-adjusted IPI in diffuse large B cell lymphoma宋佳琳, 魏小磊, 张元坤, 郝晓晓, 黄伟民, 韦祁, 魏永强, and 冯茹Guest Editor (s): 刘志红Author information Article notes Copyright and License information PMC Disclaimer510515 广州，南方医科大学南方医院血液科, Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, ChinaCorresponding author.通信作者：冯茹(Feng Ru)，Email：moc.liamtoh@6261hturReceived 2018 Feb 28Copyright 2018年版权归中华医学会所有Copyright © 2018 by Chinese Medical AssociationThis work is licensed under a Creative Commons Attribution 3.0 License (CC-BY-NC). The Copyright own by Publisher. Without authorization, shall not reprint, except this publication article, shall not use this publication format design. Unless otherwise stated, all articles published in this journal do not represent the views of the Chinese Medical Association or the editorial board of this journal.Abstract目的

比较IPI、美国国家综合癌症网络IPI（NCCN-IPI）及年龄调整的IPI（aa-IPI）三种预后分层模型在弥漫大B细胞淋巴瘤（DLBCL）患者中的预后分层能力。

方法

回顾性分析2003年1月至2012年12月311例初治DLBCL患者资料，根据治疗方案将患者分为CHOP（环磷酰胺、多柔比星、长春新碱、泼尼松）方案及利妥昔单抗（R）-CHOP方案组，分别采用IPI、NCCN-IPI及aa-IPI对DLBCL患者进行危险度分层。采用Harrell's C统计评价不同模型的预后分层能力。

结果

①311例患者中接受CHOP方案治疗者128例，接受R-CHOP方案治疗者183例。②CHOP方案组患者的5年总生存（OS）率结果显示，aa-IPI（71.0%对25.0%，P

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IPI、NCCN

IPI、NCCN

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