新生儿经外周置入中心静脉导管（PICC）技术解决了新生儿重症监护病房（NICU）住院患儿长期静脉通路的需求，技术的应用中伴随并发症发生的风险，通过规范化的操作，为新生儿提供安全的高质量的血管通路具有重要意义。美国新生儿护士协会（NANN）制定了《新生儿经外周置入中心静脉导管实践指南》并于2015年修订为《新生儿经外周置入中心静脉导管实践指南（第三版）》旨在支持床旁PICC护理实践、降低并发症的发生，促进新生儿安全。本文将对指南中新生儿PICC置管后并发症的早期识别、处理、预防推荐要点予以解读。

The peripherally inserted central catheter (PICC) in neonates has solved the long-term venous access needs of hospitalized infants in the Neonatal Intensive Care Unit (NICU) . The application of technology is accompanied by the risk of complications. Providing safe and high-quality vascular access for neonates through standardized operations is of great significance. The National Association of Neonatal Nurses (NANN) has formulated the Practice Guideline for PICC in Neonates and revised it into the the Practice Guideline for Peripherally Inserted Central Catheter in Neonates (Third Edition) in 2015, aiming to support the bedside nursing practice of neonatal PICC, reduce the occurrence of complications, and promote neonatal safety. This article interprets the recommended points for early identification, management, and prevention of complications after neonatal PICC catheterization in the guidelines.