In order to control one or many aerial cameras in reconnaissance mission cabin to work simultaneously, an integrated control system of aerial camera based on ARINC429 bus interface card has been designed. Based on simple introducing aerial camera integrated control system, ARINC429 bus interface card communication software flow charts and program design are presented in detail. The result indicates that the method is easy to be manipulated and runs steadily, the aim of reducing the number of guaranteed equipment and improving the detection efficiency has been realized. The system has applied in certain reconnaissance aero plane troops successfully.