Plastins 是一个肌动蛋白结合蛋白家族，在整个真核生物进化过程中都是保守的，并在高等真核生物的大多数组织中表达。在人类中，已鉴定出两种普遍存在的塑化蛋白亚型 (L 和 T) 。 Plastin 1 (也称为 Fimbrin) 是第三种不同的 Plastin 亚型，它在小肠中以高水平特异性表达。 L 同种型仅在造血细胞谱系中表达，而 T 同种型已在具有复制潜力的实体组织的所有其他正常细胞 (成纤维细胞、内皮细胞、上皮细胞、黑素细胞等) 中发现。 T-plastin 和 L-plastin 蛋白的 C 末端 570 个氨基酸有 83% 相同。它在 N 末端附近包含一个潜在的钙结合位点。交替剪接导致多个转录变体。[RefSeq 提供，2010 年 2 月]

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 Amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]