Glucose

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Glucose

2023-10-01 00:08| 来源: 网络整理| 查看: 265

When we eat, our digestive system breaks down the food into glucose, the body's major energy source. The most common type of simple sugar found in living organisms is glucose. When glucose is consumed and absorbed into the bloodstream, it is referred to as blood glucose or blood sugar.

The body needs glucose to function properly, and a rapid spike or fall in blood sugar levels might have negative consequences. Foods high in carbs, such as bread, fruits, and dairy products, help your body produce glucose.

Quick-release glucose supplements, which are an effective treatment for hypoglycemia, a disease characterised by a drop in blood sugar which also provides glucose on-demand. Diabetes patients must pay extra attention to their blood glucose levels.

 

Introduction

The word "glucose" is derived from the Greek word "sweet." It's a form of sugar that comes from the meals you eat and is used by your body for energy. Since it flows through your bloodstream and into your cells, it's termed blood glucose or blood sugar.

Insulin is a hormone that carries glucose from the bloodstream to cells and uses it as fuel and storage.

Diabetes individuals have higher-than-normal blood glucose levels. They don't have enough insulin or their cells don't react to it as they should. 

Glucose can be described as a simple sugar, having one aldehyde group and six carbon atoms. This monosaccharide's chemical formula can be given as C6H12O6.

It is also called dextrose and is referred to as aldohexose because it contains one aldehyde group and 6 carbon atoms. It is open in two forms, as a ring or open-chain structure. It is synthesised in the kidneys and liver of the animals. In plants, it is found in fruits and various plant parts. D- glucose is the one which occurs in a natural form of glucose. It occurs either in solid or liquid form. It is also soluble in water and also in acetic acid. It is sweet to taste and is odourless. In 1747, a German chemist named "Andreas Marggraf" isolated glucose from raisins. In 1838, Jean Baptiste Dumas coined the word glucose.

 

Properties of Glucose

Let us look at the important properties of glucose as tabulated below.

C6H12O6 chemical name or chemical name of glucose

Glucose

Chemical Formula or glucose formula

C6H12O6

Density

1.54 g/cm³

Molecular Weight or Molar Mass

180.16 g/mol

Melting Point

146 °C

Simple sugar

Monosaccharide

 

C₆H₁₂O₆ Structure

(Image to be added soon)

 

Glucose is also called aldohexose and dextrose. It is a monomer of various larger compounds like starch, cellulose, and carbohydrates, which is the earth's most abundant organic compound. Based on the following evidence, it was assigned with the structure as illustrated above.

This compound has a molecular formula of C6H12O6.

When HI is heated for a longer time, n-hexane is formed, which indicates all the 6 carbon atoms are combined in a straight chain.

The oxime is formed when glucose reacts with cyanohydrins and hydroxylamine by adding hydrogen cyanide to it. This reaction can confirm the carbonyl group's presence in glucose.

In the glucose reaction with a mild oxidising agent such as bromine water, glucose gets oxidised to a carboxylic acid that contains 6 carbon atoms, which indicates that the carbonyl group exists as an aldehyde group.

The -OH group's presence can be confirmed after the acetylation of glucose with acetic acid, which forms glucose pentaacetate.

The gluconic acid and glucose both yield saccharic acid and dicarboxylic acid on the oxidation with nitric acid. This can indicate the presence of primary alcohol.

Process of Producing Glucose in the Body

The human body processes glucose multiple times in a day, ideally.

When we start eating, our body starts working to process glucose immediately. The enzymes start the breakdown process taking the help of the pancreas - which produces hormones, including insulin, is an integral part of the way our body deals with glucose. Also, our body tips the pancreas off when we eat, which requires a release of insulin dealing with the blood sugar level rising.

However, some people cannot rely on their pancreas to jump in and do its supposed work.

One way diabetes befalls when the pancreas does not produce insulin in the proper way it should. In this case, humans need outside help (such as insulin injections) to process and regulate the glucose inside the body. Insulin resistance is another cause of diabetes, where the liver does not recognize insulin present in the body and continues to make inappropriate glucose amounts. The liver is an essential organ to control sugar because it helps with glucose storage and produces glucose when necessary.

If the body does not form the required amount of insulin, it might release free fatty acids from the fat store, which can lead to the condition known as ketoacidosis. Ketones are the waste products created when the liver breaks down fat and can be toxic in large quantities.

 

Testing the Glucose Level

Testing glucose levels is most important for people having diabetes. Many people with this condition are used to dealing with blood sugar checks as part of their everyday lives.

The most popular way to test glucose at home involves a simple blood test. Usually, a finger prick uses a small needle known as a lancet, produces a drop, and puts it onto a test strip. Then, the strip is placed into a metre, which measures the sugar levels in the blood. Usually, it can give us reading in less than 20 seconds.

 

Consequences for Unregulated Glucose Levels

There are various long-term consequences for unregulated glucose levels, leading to different conditions, as listed below.

heart disease

neuropathy

skin infections

blindness

severe dehydration

problems in the extremities and joints, especially the feet

coma

Other serious complications include hyperglycemic hyperosmolar syndrome, both conditions related to diabetes, and diabetic ketoacidosis.

 

People worried about having diabetes are advised to seek immediate help from a doctor.

Uses Of Glucose C6H12O6

It is a drug used to treat hypoglycemia (hypoglycemia) 

It is given to patients who cannot eat because it contains carbohydrate calories. 

It is used as a preliminary step in substance synthesis.

Glucose can be used in the hypoglycemia treatment (low blood sugar)

It can be used in the increased potassium level treatment in the blood (hyperkalemia)

It can be given to very sick patients and cannot eat because it produces carbohydrate calories

It is also used as a precursor for the synthesis of substances.



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