该基因编码由血小板衍生生长因子 (PDGF) 和血管内皮生长因子 (VEGF) 组成的蛋白质家族成员。编码的前原蛋白经过蛋白水解处理生成血小板衍生生长因子亚基 A，它可以与相关的血小板衍生生长因子亚基 B 同二聚化或异二聚化。这些蛋白质结合并激活 PDGF 受体酪氨酸激酶，后者在广泛的发展过程。可变剪接导致多个转录本变体。[RefSeq 提供，2015 年 10 月]

This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF Receptor Tyrosine Kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]