代表性教学科研项目：

1、 山东省自然科学基金面上项目，2024/01-2026/12，主持。

2、 国家自然科学基金青年基金，2019/01-2021/12，主持。

3、 教育部产学合作协同育人项目，2021/04-2023/03，主持。

4、 青岛市博士后应用研究项目，2020/8-2022/07，主持。

代表性论文：

[1] H. N. Chai, Y. Li, K. Yu, Z. Yuan, J. Guan, W. Tan, J. Ma, X. Zhang, G. Zhang*, Two-Site Enhanced Porphyrinic Metal–Organic Framework Nanozymes and Nano-/Bioenzyme Confined Catalysis for Colorimetric/Chemiluminescent Dual-Mode Visual Biosensing, Anal. Chem. 2023, 95, 16383-16391.

[2] H. N. Chai, K. Yu, Y. Zhao, Z. Zhang, S. Wang, C. Huang, X. Zhang, G. Zhang*, MOF-On-MOF Dual Enzyme-Mimic Nanozyme with Enhanced Cascade Catalysis for Colorimetric/Chemiluminescent Dual-Mode Aptasensing, Anal. Chem. 2023, 95, 10785-10794.

[3] G. Y. Zhang*, H. N. Chai, M. W. Tian, S. F. Zhu, L. J. Qu, X. J. Zhang*, Zirconium-Metalloporphyrin Frameworks-Luminol Competitive Electrochemiluminescence for Ratiometric Detection of Polynucleotide Kinase Activity, Anal. Chem. 2020, 92, 7354.

[4] H. Sun, J. Guan, H. N. Chai*, K. Yu, L. Qu, X. Zhang, G. Zhang*, Zinc porphyrin/MXene hybrids with phosphate-induced stimuli-responsive behavior for dual-mode fluorescent/electrochemiluminescent ratiometric biosensing, Biosense. Bioelectron. 2024, 251, 116080.

[5] K. Yu, H. N. Chai *, H. Sun, X. Xiang, H. Zhao, M. Tian, L. Qu, G. Zhang*, X. Zhang*, A fluorescence analysis model for assessing the water stability of porphyrinic metal–organic frameworks, Sens. Actuators B Chem., 2024, 401, 135046.

[6] G. Zhang, Y. Ma, H. N. Chai*, K. Yu, Y. Li, S. Wang, J. Ma, L. Qu, W. Tan*, X. Zhang, Porphyrinic metal–organic framework@alumina nanocomposite fluorescent probe: Two-stage stimuli-responsive behavior and phosphate sensing, Sens. Actuators B Chem. 2022, 370, 132395.

[7] G. Zhang*, K. Yu, B. Zhou, J. Wang, C. Zheng, L. Qu, H. N. Chai*, X. Zhang, Magnetic zirconium-based Prussian blue analog nanozyme: Enhanced peroxidase-mimicking activity and colorimetric sensing of phosphate ion, Microchim. Acta, 2022, 189, 220.

[8] H. N. Chai, Y. Ma, Z. Yuan, Y. Li, G. Liu, L. Chen, Y. Tian, W. Tan, J. Ma, G. Zhang*, A ratiometric fluorescence sensor based on carbon dots and two-dimensional porphyrinic MOFs for on-site monitoring of sulfide, Microchem. J. 2023, 185, 108288.

[9] G. Y. Zhang*, M. J. Li, K. Yu, H. N. Chai*, S. H. Xu, T. L. Xu, L. J. Qu, X. J. Zhang*, Two-Dimensional Metalloporphyrinic Framework Nanosheet-Based Dual-Mechanism-Driven Ratiometric Electrochemiluminescent Biosensing of Protein Kinase Activity, ACS Appl. Bio Mater. 2021, 4, 161.

[10] M. Li, G. Zhang*, A. Boakye, H. N. Chai*, L. Qu*, X. Zhang, Recent Advances in Metal-Organic Framework-Based Electrochemical Biosensing Applications, Front. Bioeng. Biotechnol. 9 (2021), 797067.

[11] H. N. Chai*, K. Yu, B. Liu, W. Q. Tan, G. Y. Zhang, A Highly Selective Manganese-Catalyzed Synthesis of Imines under Phosphine-Free Conditions. Organometallics, 2020, 39, 217.

[12] K. Yu, M. Li, H. Chai, Q. Liu, X. Hai, M. Tian, L. Qu, T. Xu, G. Zhang*, X. Zhang, MOF-818 nanozyme-based colorimetric and electrochemical dual-mode smartphone sensing platform for in situ detection of H2O2 and H2S released from living cells. Chem. Eng. J., 2023, 451, 138321.

[13] K. Yu, G. Zhang*, H. N. Chai, L. Qu, D. Shan, X. Zhang*, Two-stage ligand exchange in Mn(III)-based porphyrinic metal−organic frameworks for fluorescence water sensing, Sens. Actuators B Chem. 2022, 362, 131808.

[14] T. Yan, G. Zhang, K. Yu, H. N. Chai, M. Tian, L. Qu, H. Dong, X. Zhang, Smartphone light-driven zinc porphyrinic MOF nanosheets-based enzyme-free wearable photoelectrochemical sensor for continuous sweat vitamin C detection, Chem. Eng. J., 2023, 455, 140779.

代表性专利：

1、发明专利名称：一种纳米酶材料Ti-TCPP(Zn)的合成与草甘膦的比色/光电化学检测的应用，申请号：2023106405104。(第一发明人)

2、发明专利名称：一种MOFs复合材料的合成方法与草甘膦检测的应用，申请号：2023106396798。(第一发明人)

3、发明专利名称：一种MOF-on-MOF材料的合成方法与毒死蜱检测的应用，申请号：2023100421762。(第一发明人)

4、发明专利名称：一种MXene基纳米酶复合物的合成与有机磷农药检测的应用，申请号：202211422646X。(第一发明人)

5、发明专利名称：一种双阶段刺激-响应型的卟啉MOF@氧化铝纳米复合物荧光探针用于磷酸根的检测，申请号：2022103900270。(第一发明人)

6、专利授权：吡啶基桥联NNP钴配合物及其应用，专利号：ZL 202011102276.2。(第一发明人)

7、专利授权：吡啶基桥联吡唑类金属锰催化剂及其应用，专利号：ZL 202011093420.0。(第一发明人)