重复经颅磁刺激治疗中风后吞咽困难的有效性:系统评价和荟萃分析,Frontiers in Human Neuroscience

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重复经颅磁刺激治疗中风后吞咽困难的有效性:系统评价和荟萃分析,Frontiers in Human Neuroscience

2024-06-10 09:24| 来源: 网络整理| 查看: 265

Background

应用于下颌舌骨皮质区域的重复经颅磁刺激(rTMS)对中风后具有积极的临床效果。因此,我们进行了一项荟萃分析来研究 rTMS 对中风后吞咽困难患者的疗效。

Methods

根据PRISMA指南,我们检索了MEDLINE(PubMed)、Cochrane Library、Embase、Web of Science、CNKI、万方数据库。我们检索了 rTMS 治疗中风后吞咽困难的随机对照试验 (RCT) 研究,并根据纳入和排除标准进行筛选。提取了随机对照试验的特征。试验的异质性通过以下方式测量我2统计。

Results

总共有 11 项随机对照试验,涉及 463 名吞咽困难患者,符合我们的纳入标准。在我们的分析中,rTMS 与传统的吞咽练习相结合,对中风后吞咽困难具有巨大的有益作用。而且,有一个非常显着的差异(磷= 0.008)根据刺激频率(高频与低频)进行记录。此外,没有显着差异(磷= 0.53)是根据刺激部位(受影响的半球与未受影响的半球)观察到的。

Conclusions

总体而言,rTMS可以有效加速脑卒中后吞咽障碍患者吞咽功能的改善。

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The Effectiveness of Repetitive Transcranial Magnetic Stimulation for Post-stroke Dysphagia: A Systematic Review and Meta-Analysis

Background

Repetitive transcranial magnetic stimulation (rTMS) applied to the mylohyoid cortical region has positive clinical effects on post-stroke. Therefore, we conducted a meta-analysis to investigate the efficacy of rTMS for patients with post-stroke dysphagia.

Methods

According to PRISMA guidelines, we searched the databases of MEDLINE (PubMed), Cochrane Library, Embase, Web of Science, CNKI, Wangfang. We searched for studies of randomized controlled trials (RCTs) of rTMS to treat dysphagia after stroke and screened by inclusion and exclusion criteria. Features of RCTs were extracted. The heterogeneity of the trials was measured by I2 statistic.

Results

In total, 11 RCTs with 463 dysphagia patients fulfilled our inclusion criteria. In our analysis, rTMS demonstrated a great beneficial effect for post-stroke dysphagia when combined with traditional swallowing exercises. Moreover, a greatly significant difference (P = 0.008) was noted based on stimulation frequency (high frequency vs. low frequency). Additionally, no significant difference (P = 0.53) was observed based on stimulation site (affected vs. unaffected hemisphere).

Conclusions

Overall, rTMS can effectively accelerate the improvement of swallowing function in patients with post-stroke swallowing disorders.



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