对前庭系统、记忆、海马和纹状体之间相互作用的理解的最新进展,Frontiers in Neurology

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对前庭系统、记忆、海马和纹状体之间相互作用的理解的最新进展,Frontiers in Neurology

2024-07-10 08:22| 来源: 网络整理| 查看: 265

在过去的二十年中,积累的证据表明,前庭系统与大脑中与空间记忆相关的区域(例如海马体)具有广泛的联系,并且它与与自主运动控制相关的区域具有显着的相互作用,例如基底神经节中的纹状体。事实上,这些功能远非独立,人们认为纹状体和海马之间的相互作用对记忆处理很重要。除了其他神经系统疾病外,与前庭-海马-纹状体相互作用相关的数据对于阿尔茨海默病和帕金森病的理解和治疗具有重要意义。然而,证据正在迅速积累,很难跟上这些及相关领域的最新发展。

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Recent developments in the understanding of the interactions between the vestibular system, memory, the hippocampus, and the striatum

Over the last two decades, evidence has accumulated to demonstrate that the vestibular system has extensive connections with areas of the brain related to spatial memory, such as the hippocampus, and also that it has significant interactions with areas associated with voluntary motor control, such as the striatum in the basal ganglia. In fact, these functions are far from separate and it is believed that interactions between the striatum and hippocampus are important for memory processing. The data relating to vestibular-hippocampal-striatal interactions have considerable implications for the understanding and treatment of Alzheimer's Disease and Parkinson's Disease, in addition to other neurological disorders. However, evidence is accumulating rapidly, and it is difficult to keep up with the latest developments in these and related areas. The aim of this review is to summarize and critically evaluate the relevant evidence that has been published over the last 2 years (i.e., since 2021), in order to identify emerging themes in this research area.



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