冰片在心脑血管疾病中的作用:药理作用、机制和治疗,Pharmacological Research

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冰片在心脑血管疾病中的作用:药理作用、机制和治疗,Pharmacological Research

2024-07-09 13:21| 来源: 网络整理| 查看: 265

随着全球人口老龄化进程的加快,心脑血管疾病(CVDs)的发病率呈上升趋势。它已成为人类死亡的主要原因。冰片(BO)作为一种天然药物,不仅具有抗炎、抗氧化、抗凋亡、抗凝血等作用,改善能量代谢,还可以促进药物通过各种生理屏障进入靶器官或组织,如如血脑屏障(BBB)、粘膜、皮肤。因此,它对各种心血管疾病具有显着的治疗作用,这一点已在大量研究中得到证实。然而,BO对心血管疾病的药理作用和机制尚未得到充分研究。因此,本综述总结了 BO 的药理作用和可能的机制,

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Borneol in cardio-cerebrovascular diseases: Pharmacological actions, mechanisms, and therapeutics

With the coming acceleration of global population aging, the incidence rate of cardio-cerebrovascular diseases (CVDs) is increasing. It has become the leading cause of human mortality. As a natural drug, borneol (BO) not only has anti-inflammatory, anti-oxidant, anti-apoptotic, anti-coagulant activities and improves energy metabolism but can also promote drugs to enter the target organs or tissues through various physiological barriers, such as the blood-brain barrier (BBB), mucous membrane, skin. Thus, it has a significant therapeutic effect on various CVDs, which has been confirmed in a large number of studies. However, the pharmacological actions and mechanisms of BO on CVDs have not been fully investigated. Hence, this review summarizes the pharmacological actions and possible mechanisms of BO, which provides novel ideas for the treatment of CVDs.



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