Research and teaching have an array of unique hazards that reflects both the variety and continuous evaluation of their operation. These include technical, physical, chemical, or biological hazards. We are reporting a laboratory accident involving acryloyl chloride (chemical hazard), its consequences, safety precautions, and the lesson learned from this incident. Acryloyl chloride is a highly toxic and volatile liquid. After being accidentally exposed to acryloyl chloride, a victim experienced blackout, headache, dizziness, tiredness, nose bleeding, persistent burning of the eyes, and intense nausea and vomiting. A victim reported two distinct hazardous effects, namely, nose bleeding and stomach ulcers, which were not mentioned in the SDS of acryloyl chloride. To avoid further exacerbation of consequences of acryloyl chloride accident, it may be preferable to initiate steroidal therapy along with symptomatic treatment from the start. The accidental consequences and lessons learned from this tragedy will serve as guiding factors for research scholars, postdoctoral fellows, principal investigators (PI), safety professionals, institutions, occupational health nurses, physicians, and toxicologists to prevent anything similar from happening again in the future.