代表性论文：（*通讯作者）

1. Zhang Y, Zhao M, Gao H, Yu G, Zhao Y*, Yao F*, Yang W*. MAPK signaling-induced Phosphorylation and Subcellular Translocation of PDHE1α Promotes Tumor Immune Evasion. Nat Metab. 2022 Mar;4(3):374-388.

2. Wu S, Cao R, Tao B, Wu P, Peng C, Gao H, Liang J*, Yang W*. Pyruvate Facilitates FACT-Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma. Adv Sci (Weinh). 2022 Jan 20;e2104055.

3. Zhang Y, Yu H, Zhang J, Gao H, Wang S, Li S, Wei P, Liang J, Yu G, Wang X*, Li X*, Li D* and Yang W*. Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine. J Clin Invest, 2021 Nov 1;131(21):e146187.

4. Wang X, Liu R, Zhu W, Qu X, Yu H, Chu H, Zhang Y, Zhu W, Wu X, Gao H, Tao B, Li W, Liang J, Li G*, Yang W*. α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development. Mol Cell, 2019 Oct 3;76(1):148-162

5. Wang X, Liu R, Zhu W, Chu H, Yu H, Wei P, Wu X, Zhu H, Gao H, Liang J, Li G*, Yang W*. UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis. Nature, 2019 Jul; 571(7763):127-131.

6. Liu R, Li W, Tao B, Wang X, Yang Z, Zhang Y, Wang C, Liu R, Gao H, Liang J, Yang W*. Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance. Nat Commun, 2019 Mar 1; 10(1):991.

7. Jin G, Zhang Y, Cong W, Wu X, Wang X, Wu S, Wang S, Zhou W, Yuan S, Gao H, Yu G*, Yang W*. Phosphoglucomutase 1 Inhibits Hepatocellular Carcinoma Progression by Regulating Glucose Trafficking. PLOS Biol, 2018, 16(10): e2006483.

8. Zhang Y, Yu G, Chu H, Wang X, Xiong L, Cai G, Liu R, Gao H, Tao B, Li W, Li G*, Liang J, Yang W*. Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis. Mol Cell, 2018 July; 71:1-15

9. Liang J, Cao R, Wang X, Zhang Y, Wang P, Gao H, Li C, Yang F, Zeng R, Wei P, Li D, Li W and Yang W*. Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2. Cell Res, 2017 Mar; 27(3):329-351.

10. Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, Wang L, Yang W*, Lu Z*. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun, 2016 Aug 3; 7:12431.

11. Yang W, Zheng Y, Xia Y, Ji H, Cote G, Aldape K, Chen X, Lu Z*. ERK1/2-dependent nuclear translocation of PKM2 promotes the Warburg effect. Nat Cell Biol, 2013 Jan; 15(1):124.

12. Yang W, Xia Y, Zheng Y, Bu W, Yung W, Cote G, Aldape K, Li Y, Verma I, Chiao P, Lu Z*. EGFR-induced NF-κB activation upregulates PKM2 expression and promotes the Warburg effect. Mol Cell, 2012 Dec 14; 48(5):771-84.

13. Yang W, Xia Y, Hawke D, Li X, Liang J., Xing D, Aldape K, Hunter T, Yung W, Lu Z*. PKM2 phosphorylates Histone H3 and promotes gene transcription and tumorigenesis. Cell, 2012 Aug 17; 150(4):685-96.

14. Yang W, Xia Y, Ji H, Zheng Y., Liang J., Huang W, Gao X, Aldape K, and Lu Z*. Nuclear PKM2 regulates beta-catenin transactivation upon EGF stimulation. Nature, 2011 Dec 1; 480(7375):118-22.