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Cell linesHematopoietic cell linesCell lines
Name
Description of cell line
Original reference
Origin
Sex & Age
Source
Cellosaurus (ExPaSy)
Brain
AF22
iPS derived Neuroepithelia stem (NES) cell line
Falk et al., PLoS One 7(1) (2012)
Skin
Female, 36
NA
Uncategorised
U-251MG
Glioblastoma cell line
Westermark B., Int J Cancer12: 438 (1973)
Brain
Male
BW1
CVCL_0021Cancer cell line
GAMG
Glioblastoma cell line
Akslen et al, Anticancer Res. 8(4): 797-803 (1988)
Female, 42
DSMZ
CVCL_1226Cancer cell line
SH-SY5Y
Metastatic neuroblastoma, clonal subline of neuroepithelioma cell line SK-N-SH
Biedler et al., Cancer Res 33: 2643 (1973)
Bone marrow
Female, 4
DSMZ
CVCL_0019Cancer cell line
Eye
HTCEpi
Telomerase-immortalized corneal epithelial cell line
Robertson et al., Invest Ophthalmol Vis Sci 46(2): 470-478 (2005)
Cornea
Male, 62
Evercyte
CVCL_AQ44Telomerase immortalized cell line
HTERT-RPE1 (serum starved)
Retinal pigment epithelial cells immortalized with hTERT
Rambhatla L et al.. Invest Ophthalmol Vis Sci. 43(5):1622-30. (2002)
Retina, eye
Female, 1
CVCL_4388Telomerase immortalized cell line
HTERT-RPE1
Retinal pigment epithelial cells immortalized with hTERT
Rambhatla L et al.. Invest Ophthalmol Vis Sci. 43(5):1622-30. (2002)
Retina, eye
Female, 1
CVCL_4388Telomerase immortalized cell line
Proximal digestive tract
OE19
Esophageal adenocarcinoma cell line
PMID: 9010035
Esophagus
Male, 72
DSMZ
CVCL_1622Cancer cell line
Gastrointestinal tract
CACO-2
Colon adenocarcinoma cell line
Fogh J., et al. J. Natl. Cancer Inst. 58: 209 (1977)
Colon
Male, 72
DSMZ
CVCL_0025Cancer cell line
Liver & Gallbladder
Hep-G2
Hepatocellular carcinoma cell line
Aden et al., Nature 282: 615 (1979)
Liver
Male, 15
DSMZ
CVCL_0027Cancer cell line
Kidney & Urinary bladder
RT-4
Urinary bladder transitional cell carcinoma cell line
Rigby et al., Br J Cancer 24: 746 (1970)
Urinary bladder
Male, 63
DSMZ/ECACC
CVCL_0036Cancer cell line
RPTEC/TERT1
Proximal tubular epithelial cell line
Wieser et al., Am J Physiol Renal Physiol 295(5): 1365-1375 (2008)
Human kidney cortex
Male
Evercyte
CVCL_K278Telomerase immortalized cell line
HEK293
Embryonal kidney cell line, transformed by adenovirus type 5
Graham et al., J Gen Virol 36: 59 (1977)
Embryonal kidney
Female
DSMZ
CVCL_0045Transformed cell line
Male reproductive system
SuSa
Testicular germ cell tumor
PMID: 593370
Testis
Male, 30
DSMZ
CVCL_L280Cancer cell line
PC-3
Metastatic poorly differentiated prostate adenocarcinoma cell line
Kaighn et al., Invest Urol 17: 16-23 (1979)
Bone marrow
Male, 62
DSMZ
CVCL_0035Cancer cell line
Skin
HaCaT
Keratinocyte cell line
Boukamp et al., J Cell Biol Mar 106(3): 761 (1988)
Skin
Male
NEF2
CVCL_0038Spontaneously immortalized cell line
SK-MEL-30
Metastatic malignant melanoma cell line
Carey et al., Proc Natl Acad Sci USA 73: 3278 (1976)
Subcutis
Male, 67
DSMZ
CVCL_0039Cancer cell line
A-431
Epidermoid carcinoma cell line
Giard et al., J Natl Cancer Inst 51: 1417 (1973)
Skin
Female, 85
DSMZ
CVCL_0037Cancer cell line
Lung
A-549
Lung carcinoma cell line
Giard et al., J Natl Cancer Inst 51: 1417 (1973)
Lung
Male, 58
DSMZ
CVCL_0023Cancer cell line
HBEC3-KT
Immortalized human bronchial epithelial cell line
Central lung bronchiole
Female, 65
Evercyte
CVCL_X491Telomerase immortalized cell line
Female reproductive system
HTERT-HME1
Immortalized mammary epithelial cell line
Mammary gland
Female, 53
Evercyte
CVCL_3383Telomerase immortalized cell line
HeLa
Cervical epithelial adenocarcinoma cell line
Scherer et al., J Exp Med 97: 695 (1953)
Cervix
Female, 31
DSMZ
CVCL_0030Cancer cell line
MCF-7
Metastatic breast adenocarcinoma cell line
Soule et al., J Natl Cancer Inst 51: 1409 (1973)
Pleural effusion
Female, 69
DSMZ
CVCL_0031Cancer cell line
EFO-21
Metastatic ovarian serous cystadenocarcinoma cell line
Simon et al., J Natl Cancer Inst 70: 839 (1983)
Ascites
Female, 56
DSMZ
CVCL_0029Cancer cell line
SiHa
Cervical squamous cell carcinoma cell line, integrated 1-2 copies of HPV16
Friedl F. et al.Proc., Soc. Exp. Biol. Med. 135: 543-545 (1970)
Cervix
Female, 55
LGC/ATCC
CVCL_0032Cancer cell line
Endothelial
HUVEC/TERT2
Umbilical vein endothelial cell line
NA
Umbilical vein
Female
Evercyte
CVCL_9Q53Telomerase immortalized cell line
Mesenchymal
Rh30
Metastatic rhabdomyosarcoma cell line
Douglass et al., Cytogenet Cell Genet 45: 148-155 (1987)
Bone marrow
Male, 17
DSMZ
CVCL_0041Cancer cell line
ASC52telo
Adipose tissue-derived mesenchymal stem cell line
Wolbank S. et al., Tissue Eng Part A: Jul;15(7):1843-54 (2009)
Adipose tissue
Female
Evercyte
CVCL_U602Telomerase immortalized cell line
U2OS
Osteosarcoma cell line
Ponten J., Saksela E. Int. J. Cancer 2: 434 (1967)
Bone
Female, 15
LGC/ATCC
CVCL_0042Cancer cell line
BJ [Human fibroblast]
Adherent fibroblast cell line
Bodnar AG., et al. Science 279: 349-352 (1998)
Foreskin
Male
LGC/ATCC
CVCL_3653Finite cell line
FHDF/TERT166
Immortalized human foreskin fibroblast cell line
Foreskin
Male
Evercyte
CVCL_GZ73Telomerase immortalized cell line
HBF/TERT88
Adherent brain fibroblast cell line
NA
Brain
Female
Evercyte
CVCL_9Q52Telomerase immortalized cell line
LHCN-M2
Adherent myoblast cell line
Zhu et al., Aging Cell 6(4): 515-523 (2007)
Satellite cells (from pectoralis major muscle)
Male, 41
Evercyte
CVCL_8890Telomerase immortalized cell line
Lymphoid
HTEC/SVTERT24-B
Immortalized thymic epithelial cell line
Thymus
Female
Evercyte
CVCL_JM27Transformed cell line
REH**
Pre-B cell leukemia cell line (ALL, first relapse)
Rosenfeld et al., Nature 267: 841–3 (1977)
Peripheral blood
Female, 15
DSMZ
CVCL_1650Cancer cell line
HDLM-2
Hodgkin lymphoma cell line
Drexler et al., Leuk Res 10: 487 (1986)
Pleural effusion
Male, 74
DSMZ
CVCL_0009Cancer cell line
JURKAT
T-cell leukemia cell line
Peripheral blood
Male, 14
DSMZ
CVCL_0065Cancer cell line
Myeloid
HAP1
Haploid karyotype cell line from Chronic myelogenous leukemia
Carette et al., Nature 477(7364): 340-343 (2011)
Leukemia
Male
Horizon Discovery
CVCL_Y019Cancer cell line
HEL
Erythroleukemia cell line (AML M6 in relapse after treatment for Hodgkin's disease)
Martin et al., Science 216: 1233 (1982)
Peripheral blood
Male, 30
DSMZ
CVCL_0001Cancer cell line
NB4
Acute promyelocytic leukemia (APL) cell line
Lanotte et al., Blood 77: 1080 (1991)
Bone marrow
Female, 23
DSMZ
CVCL_0005Cancer cell line
THP-1
Acute monocytic leukemia (AML) cell line
Tsuchiya et al., Int J Cancer 26: 171 (1980)
Peripheral blood
Male, 1
DSMZ
CVCL_0006Cancer cell line
K-562
Chronic myeloid leukemia (CML) cell line
Lozzio et al., J Natl Cancer Inst 50: 535 (1973)
Pleural effusion
Female, 53
DSMZ
CVCL_0004Cancer cell line
Mouse
NIH 3T3
Mouse embryonal fibroblast cell line
Aaronson et al., J Cell Physio 72(2): 141-148 (1968)
Embryo
DSMZ
CVCL_0594Spontaneously immortalized cell line
Notes
* Allen M, Bjerke M, Edlund H, Nelander S and Westermark B: Origin of the U87MG glioma cell line: Good news and bad news. Science Translational Medicine 31 Aug 2016: Vol. 8, Issue 354, pp. 354. DOI: 10.1126/scitranslmed.aaf6853
** REH was previously listed as KM3. Due to misidentification, KM3 has been deleted from the DSMZ catalogue and the true identity is REH.
DSMZ - False leukemia and lymphoma cell lines.
Drexler et al., False leukemia-lymphoma cell lines: An update on over 500 cell lines. Leukemia 17: 416-426 (2003)
Source information
Prof. Bengt Westermark, Uppsala University, Uppsala, SwedenProf. Norbert E Fusenig, DKFZ, Heidelberg, Germany
Hematopoietic cell lines Schematic description of hematopoietic differentiation lineages, and cellular origin for hematopoietic cell lines.
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