Although the SPICE models used in a SPICE simulation can greatly affect the accuracy of the results, simulation settings also contribute to varying degrees of accuracy. SPICE simulation options generally allow the user to gain more accuracy in the results at the cost of the speed of the simulation.

To understand the tradeoff between speed and accuracy in SPICE simulation one must consider a number of factors. SPICE simulation was created over 30 years go and around that time a typical computer had less power than the average microwave oven did thirty years later. Computing power was very expensive. The simulation of a circuit to the highest degree of accuracy could have taken longer and cost more money than building the actual circuit to see the results. Also, consider that the broad purpose of circuit simulation is to augment basic hand calculations and predict general circuit behavior. With these considerations in mind, the designers of SPICE created a program that could produce reasonably accurate results in a cost-effective manner. They also included many options to allow engineers to customize the accuracy of a simulation.

As computing power has increased exponentially over the years, so have the complexity of circuit designs being simulated. Speed and accuracy are still important factors to consider when simulating circuits.