This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

[中文简述(自动翻译):]此基因是配对盒（PAX）家族的转录因子的成员。此基因家族成员通常包含配对盒结构域，八肽，以及一个成对型同源异型域。这些基因发挥胎儿的发育和肿瘤生长过程中的关键作用。配对盒7基因的具体功能不明，但推测由于这个基因与叉头域家族成员的融合已经与腺泡型横纹肌肉瘤相关的涉及抑制肿瘤。已发现该基因编码不同亚型三个抄本变形。 [由RefSeq的，2008年9月提供]