美沙拉嗪，也称为 5-氨基水杨酸 (5-ASA)，是一种来自非甾体抗炎药 (NSAID) 家族的合成药物，用于治疗胃肠道炎症性疾病。然而，由于其药理作用，5-ASA 也被用于各种其他疾病，但它们通常散布在各种出版物中，这可能会限制该药物的进一步研究和临床使用。本综述总结了已发表的关于 5-ASA 的生物学和药理作用的信息，旨在确定其抗氧化作用和药用价值。使用 Web of Science、PubMed、Elsevier、Wiley Online Library、Springer、Google Scholar 等主要数据库收集了 1987 年至 2021 年 2 月的 5-ASA 数据。根据研究，5-ASA的药理和生物学作用包括治疗炎症性肠病，以及抗氧化、抗炎、抗菌、抗真菌、抗癌、抗淀粉样蛋白、胃保护（胃保护）和抗憩室病的特性。大量药理学研究表明，5-ASA 是一种具有很高治疗潜力的抗氧化和抗溃疡化合物，如果发现合适的剂量，其化学结构会发生变化并优化其有效性，5-ASA 已被用于实验性治疗。其他疾病。

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Mesalazine, also known as 5-aminosalicylic acid (5-ASA), is a synthetic drug from the family of nonsteroidal anti-inflammatory drugs (NSAIDs) used for inflammatory diseases of the gastrointestinal tract. However, 5-ASA has also been used for various other diseases due to its pharmacological effects, but they are usually scattered across various publications, which may limit further research and clinical use of this drug. This review is a summary of published information on the biological and pharmacological effects of 5-ASA with the aim of identifying its anti-oxidant role and medicinal use. 5-ASA data have been collected from 1987 to February 2021 using major databases such as Web of Science, PubMed, Elsevier, Wiley Online Library, Springer, Google Scholar, etc. According to research, the pharmacological and biological effects of 5-ASA include treatment of inflammatory bowel disease, and anti-oxidant, anti-inflammatory, antibacterial, antifungal, anticancer, anti-amyloid, gastric protection (gastroprotective), and antidiverticulosis properties. Numerous pharmacological studies have shown that 5-ASA is an anti-oxidant and anti-ulcer compound with high therapeutic potential that, if the appropriate dose is discovered, its chemical structure changes and its effectiveness is optimized, 5-ASA has been used experimentally for other diseases.