HINDER, IMPEDE, OBSTRUCT, BLOCK mean to interfere with the activity or progress of. 

hinder

to limit the ability of someone to do something, or to limit the development of something 阻碍，妨碍

HINDER stresses causing harmful or annoying delay or interference with progress. 

// rain hindered the climb  大雨阻碍了攀登

// High winds have hindered firefighters in their efforts to put out the blaze. 大风阻碍消防队员扑灭大火。

// Her progress certainly hasn't been hindered by her lack of experience. 经验不足当然没有妨碍她的进步。

impede

to interfere with or slow the progress of 妨碍，阻碍；阻止

IMPEDE implies making forward progress difficult by clogging, hampering, or fettering. 

// tight clothing that impedes movement 妨碍运动的紧身衣

// Although he's shy, it certainly hasn't impeded his career in any way. 尽管他很害羞，但这显然一点儿也没有妨碍他的事业。

// Pompeo vowed to limit the ability of Chinese cloud service providers to collect, store, and process data in the U.S., an effort could impede the U.S. operations of tech giants including Alibaba, Tencent, and Baidu.

— Fortune, "The U.S. has long decried China’s ‘Great Firewall’—now it’s building its own," 6 Aug. 2020

obstruct

to hinder from passage, action, or operation 阻塞，阻挡（道路、通道、入口等），阻碍，阻止，妨碍

OBSTRUCT implies interfering with something in motion or in progress by the sometimes intentional placing of obstacles in the way.  

// The view was obstructed by billboards, 这个风景被广告牌遮挡 

// The view of the stage was obstructed by a pillar. 一根柱子挡住了视线看舞台。

// An accident is obstructing traffic. 一场事故堵塞了交通。

// Constant interruptions obstruct our progress. 不断的干扰阻碍了我们的进步。

// was charged with obstructing justice by lying to investigators 被控通过向调查员撒谎来妨碍司法公正

block

to prevent movement through something,  to stop something from happening or succeeding 堵塞，阻挡，阻碍，妨碍

BLOCK implies complete obstruction to passage or progress.

// a landslide blocked the road 滑坡挡住了道路

// A fallen tree is blocking the road. 一棵倒下的树挡住了路。

// She was very talented and I felt her parents were blocking her progress. 她很有才华，我觉得她的父母妨碍了她的发展。

// A group of politicians blocked the proposal. 一群政客使该提案流产了。