摘要

麦角硫因 (EGT) 是一种高价值的天然含硫氨基酸，已被证明具有极强的抗氧化和细胞保护活性。目前，EGT已广泛应用于食品、功能食品、化妆品、医药等行业，但其收率低仍是亟待克服的问题。本文简要介绍了EGT的生物学活性和功能，阐述了其在食品、功能食品、化妆品、医药等行业的具体应用，介绍并比较了EGT的主要生产方法和在不同微生物中的生物合成途径。此外，还讨论了使用基因和代谢工程方法来提高 EGT 的产量。此外，

"点击查看英文标题和摘要"

Abstract

Ergothioneine (EGT) is a high-value natural sulfur-containing amino acid and has been shown to possess extremely potent antioxidant and cytoprotective activities. At present, EGT has been widely used in food, functional food, cosmetics, medicine, and other industries, but its low yield is still an urgent problem to overcome. This review briefly introduced the biological activities and functions of EGT, and expounded its specific applications in food, functional food, cosmetic, and medical industries, introduced and compared the main production methods of EGT and respective biosynthetic pathways in different microorganisms. Furthermore, the use of genetic and metabolic engineering methods to improve EGT production was discussed. In addition, the incorporation of some food-derived EGT-producing strains into fermentation process will allow the EGT to act as a new functional factor in the fermented foods.