由该基因编码的蛋白质是 ATP 结合盒 (ABC) 转运蛋白超家族的成员。 ABC 蛋白可跨细胞外膜和细胞内膜转运各种分子。 ABC 基因分为七个不同的亚家族 (ABC1、MDR/TAP、MRP、ALD、OABP、GCN20、White) 。这种完整的转运蛋白是参与多重耐药性的 MRP 亚家族的成员。这种蛋白质作为多特异性有机阴离子转运蛋白发挥作用，以氧化型谷胱甘肽、半胱氨酰白三烯和活化的黄曲霉毒素 B1 作为底物。这种蛋白质还转运类固醇激素和胆汁盐的葡糖苷酸和硫酸结合物。已经描述了该基因的可变剪接变体，但其全长性质未知。[RefSeq 提供，2012 年 4 月]

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid Hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]