乙酰辅酶 A 乙酰转移酶 2(ACAT2)基因

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乙酰辅酶 A 乙酰转移酶 2(ACAT2)基因

2023-12-01 14:22| 来源: 网络整理| 查看: 265

功能概要

该基因的产物是一种参与脂质代谢的酶,它编码胞质乙酰乙酰辅酶 A 硫解酶。该基因显示与小鼠和人类 TCP1 基因的 3-prime 区域互补重叠。这些基因编码在相反的 DNA 链上,并且转录方向相反。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供,2014 年 12 月]

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]



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