COSMIC v99, released 28-NOV-23
COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the world's
largest and most comprehensive resource for exploring the impact of
somatic mutations in human cancer.
Start using COSMIC by searching for a gene, cancer type, mutation, etc.
below.
Projects
COSMIC is divided into several distinct projects, each presenting a
separate dataset or view of our data:
COSMIC
The core of COSMIC, an expert-curated database of somatic mutations
Cell Lines Project
Mutation profiles of over 1,000 cell lines used in cancer research
COSMIC-3D
An interactive view of cancer mutations in the context of 3D structures
Cancer Gene Census
A catalogue of genes with mutations that are causally implicated in cancer
Cancer Mutation Census
Classification of genetic variants driving cancer
Actionability
Mutations actionable in precision oncology
Data curation
Gene Curation —
details of our manual curation process
Gene Fusion Curation —
details of our curation process for gene fusions
Genome Annotation —
information on the annotation of genomes
Drug Resistance —
curation of mutations conferring drug resistance
Mutational Signatures —
a census of mutation signatures in cancer
Actionability —
Mutations actionable in precision oncology
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